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Piccirilli, Joseph A.
One or more keywords matched the following items that are connected to Piccirilli, Joseph A.
Item TypeName
Concept Base Sequence
Academic Article RNA catalysis by a group I ribozyme. Developing a model for transition state stabilization.
Academic Article Metal ion catalysis in the Tetrahymena ribozyme reaction.
Academic Article Aminoacyl esterase activity of the Tetrahymena ribozyme.
Academic Article Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis.
Academic Article Abortive products as initiating nucleotides during transcription by T7 RNA polymerase.
Academic Article Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage.
Academic Article Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns.
Academic Article Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosides.
Academic Article Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet.
Academic Article A C-nucleotide base pair: methylpseudouridine-directed incorporation of formycin triphosphate into RNA catalyzed by T7 RNA polymerase.
Academic Article Identification of an active site ligand for a group I ribozyme catalytic metal ion.
Academic Article Synthesis of 2'-C-difluoromethylribonucleosides and their enzymatic incorporation into oligonucleotides.
Academic Article Synthetic antibodies for specific recognition and crystallization of structured RNA.
Academic Article Structure and function converge to identify a hydrogen bond in a group I ribozyme active site.
Academic Article Ribozyme-catalyzed and nonenzymatic reactions of phosphate diesters: rate effects upon substitution of sulfur for a nonbridging phosphoryl oxygen atom.
Academic Article Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Academic Article Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
Academic Article Linkage between substrate recognition and catalysis during cleavage of sarcin/ricin loop RNA by restrictocin.
Academic Article The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues.
Academic Article Synthesis of 2'-N-methylamino-2'-deoxyguanosine and 2'-N,N-dimethylamino-2'-deoxyguanosine and their incorporation into RNA by phosphoramidite chemistry.
Academic Article Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites.
Academic Article Recognition of guanosine by dissimilar tRNA methyltransferases.
Academic Article Structural inference of native and partially folded RNA by high-throughput contact mapping.
Academic Article A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.
Academic Article General acid-base catalysis mediated by nucleobases in the hairpin ribozyme.
Academic Article A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore.
Academic Article Evidence for a group II intron-like catalytic triplex in the spliceosome.
Academic Article Determination of hepatitis delta virus ribozyme N(-1) nucleobase and functional group specificity using internal competition kinetics.
Academic Article Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.
Academic Article Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Academic Article Laboratory evolution of artificially expanded DNA gives redesignable aptamers that target the toxic form of anthrax protective antigen.
Academic Article Synthesizing topological structures containing RNA.
Academic Article A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Academic Article Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Academic Article The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes.
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